U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination
You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 1 to 20 of 2142

1.
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel–Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α Stabilizers
Lan Phuong Vu, Claudia J. Diehl, Ryan Casement, Adam G. Bond, Christian Steinebach, Nika Strašek, Aleša Bricelj, Andrej Perdih, Gregor Schnakenburg, Izidor Sosič, Alessio Ciulli, Michael Gütschow
J Med Chem. 2023 Sep 28; 66(18): 12776–12811. Published online 2023 Sep 14. doi: 10.1021/acs.jmedchem.3c00434
PMCID:
PMC10544018
ArticlePDF–12M
2.
Yb(OTf)3-Catalyzed and Di-tert-butyl Dicarbonate-Mediated Decarboxylative Etherification and Esterification Reactions
Arshpreet Kaur, Arshdeep Pannu, Deshkanwar S. Brar, Surinder K. Mehta, Deepak B. Salunke
ACS Omega. 2020 Aug 25; 5(33): 21007–21014. Published online 2020 Aug 13. doi: 10.1021/acsomega.0c02516
PMCID:
PMC7450632
ArticlePDF–1.4M
3.
Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors
S. Kaleem Ahmed, Nicole N. Haese, Jaden T. Cowan, Vibha Pathak, Omar Moukha-Chafiq, Valerie J. Smith, Kevin J. Rodzinak, Fahim Ahmad, Sixue Zhang, Kiley M. Bonin, Aaron D. Streblow, Cassilyn E. Streblow, Craig N. Kreklywich, Clayton Morrison, Sanjay Sarkar, Nathaniel Moorman, Wes Sander, Robbie Allen, Victor DeFilippis, Babu L. Tekwani, Mousheng Wu, Alec J. Hirsch, Jessica L. Smith, Nichole A. Tower, Lynn Rasmussen, Robert Bostwick, Joseph A. Maddry, Subramaniam Ananthan, John M Gerdes, Corinne E. Augelli-Szafran, Mark J. Suto, Thomas E. Morrison, Mark T. Heise, Daniel N. Streblow, Ashish K. Pathak
J Med Chem. Author manuscript; available in PMC 2022 Dec 22.
Published in final edited form as: J Med Chem. 2021 Apr 22; 64(8): 4762–4786. Published online 2021 Apr 9. doi: 10.1021/acs.jmedchem.0c02183
PMCID:
PMC9774970
ArticlePDF–5.5M
4.
Tranylcypromine-based LSD1 Inhibitors: Structure-Activity Relationship, Antiproliferative Effect in Leukemias and Gene Target Modulation
Rossella Fioravanti, Annalisa Romanelli, Nicola Mautone, Elisabetta Di Bello, Annarita Rovere, Davide Corinti, Clemens Zwergel, Sergio Valente, Dante Rotili, Oronza A. Botrugno, Paola Dessanti, Stefania Vultaggio, Paola Vianello, Anna Cappa, Claudia Binda, Andrea Mattevi, Saverio Minucci, Ciro Mercurio, Mario Varasi, Antonello Mai
ChemMedChem. Author manuscript; available in PMC 2021 Apr 3.
Published in final edited form as: ChemMedChem. 2020 Apr 3; 15(7): 643–658. Published online 2020 Feb 14. doi: 10.1002/cmdc.201900730
PMCID:
PMC7125024
ArticlePDF–1.1M
5.
Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5 (WDR5)–MYC Protein–Protein Interaction
Jonathan D. Macdonald, Selena Chacón Simon, Changho Han, Feng Wang, J. Grace Shaw, Jennifer E. Howes, Jiqing Sai, Joannes P. Yuh, Demarco Camper, Bethany M. Alicie, Joseph Alvarado, Sameer Nikhar, William Payne, Erin R. Aho, Joshua A. Bauer, Bin Zhao, Jason Phan, Lance R. Thomas, Olivia W. Rossanese, William P. Tansey, Alex G. Waterson, Shaun R. Stauffer, Stephen W. Fesik
J Med Chem. Author manuscript; available in PMC 2019 Dec 27.
Published in final edited form as: J Med Chem. 2019 Dec 26; 62(24): 11232–11259. Published online 2019 Dec 5. doi: 10.1021/acs.jmedchem.9b01411
PMCID:
PMC6933084
ArticlePDF–3.1M
6.
Synthesis of 5-(Fluoroalkyl)isoxazole Building Blocks by Regioselective Reactions of Functionalized Halogenoximes
Bohdan A. Chalyk, Kateryna V. Hrebeniuk, Yulia V. Fil, Dr. Konstantin S. Gavrilenko, Dr. Alexander B. Rozhenko, Bohdan V. Vashchenko, Dr. Oleksandr V. Borysov, Dr. Angelina V. Biitseva, Dr. Pavlo S. Lebed, Iulia Bakanovych, Dr. Yurii S. Moroz, Dr. Oleksandr O. Grygorenko
J Org Chem. Author manuscript; available in PMC 2020 Dec 20.
Published in final edited form as: J Org Chem. 2019 Dec 20; 84(24): 15877–15899. Published online 2019 Oct 30. doi: 10.1021/acs.joc.9b02264
PMCID:
PMC7341682
ArticlePDF–2.2M
7.
Heterobifunctional Ligase Recruiters Enable pan-Degradation of Inhibitor of Apoptosis Proteins
Yuen Lam Dora Ng, Aleša Bricelj, Jacqueline A. Jansen, Arunima Murgai, Kirsten Peter, Katherine A. Donovan, Michael Gütschow, Jan Krönke, Christian Steinebach, Izidor Sosič
J Med Chem. 2023 Apr 13; 66(7): 4703–4733. Published online 2023 Mar 30. doi: 10.1021/acs.jmedchem.2c01817
PMCID:
PMC10108347
ArticlePDF–6.0M
8.
Design, Synthesis, Crystal Structure, In Vitro and In Silico Evaluation of New N′-Benzylidene-4-tert-butylbenzohydrazide Derivatives as Potent Urease Inhibitors
Sajjad Ahmad, Momin Khan, Najeeb Ur Rehman, Muhammad Ikram, Sadia Rehman, Mahboob Ali, Jalal Uddin, Ajmal Khan, Aftab Alam, Ahmed Al-Harrasi
Molecules. 2022 Oct; 27(20): 6906. Published online 2022 Oct 14. doi: 10.3390/molecules27206906
PMCID:
PMC9608490
ArticlePDF–7.5M
9.
Recent Advances in Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds
Arseni Borissov, Yogesh Kumar Maurya, Liliia Moshniaha, Wai-Shing Wong, Marika Żyła-Karwowska, Marcin Stępień
Chem Rev. 2022 Jan 12; 122(1): 565–788. Published online 2021 Dec 1. doi: 10.1021/acs.chemrev.1c00449
PMCID:
PMC8759089
ArticlePDF–46M
10.
Synthesis and insecticidal activity of diacylhydrazine derivatives containing a 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole scaffold
Yanyan Wang, Fangzhou Xu, Gang Yu, Jun Shi, Chuanhui Li, A’li Dai, Zhiqian Liu, Jiahong Xu, Fenghua Wang, Jian Wu
Chem Cent J. 2017; 11: 50. Published online 2017 Jun 5. doi: 10.1186/s13065-017-0279-z
PMCID:
PMC5459783
ArticlePDF–1.3M
11.
Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis
Dana M. Klug, Eftychia M. Mavrogiannaki, Katherine C. Forbes, Lisseth Silva, Rosario Diaz-Gonzalez, Guiomar Pérez-Moreno, Gloria Ceballos-Pérez, Raquel Garcia-Hernández, Cristina Bosch-Navarrete, Carlos Cordón-Obras, Claudia Gómez-Liñán, Andreu Saura, Jeremiah D. Momper, Maria Santos Martinez-Martinez, Pilar Manzano, Ali Syed, Nelly El-Sakkary, Conor R. Caffrey, Francisco Gamarro, Luis Miguel Ruiz-Perez, Dolores Gonzalez Pacanowska, Lori Ferrins, Miguel Navarro, Michael P. Pollastri
J Med Chem. Author manuscript; available in PMC 2022 Jul 8.
Published in final edited form as: J Med Chem. 2021 Jul 8; 64(13): 9404–9430. Published online 2021 Jun 22. doi: 10.1021/acs.jmedchem.1c00674
PMCID:
PMC8412142
ArticlePDF–1.3M
12.
Diphenylcarbene Protected by Four ortho-Iodine Groups: An Unusually Persistent Triplet Carbene
Katsuyuki Hirai, Kana Bessho, Kosaku Tsujita, Toshikazu Kitagawa
Molecules. 2016 Nov; 21(11): 1545. Published online 2016 Nov 15. doi: 10.3390/molecules21111545
PMCID:
PMC6272868
ArticlePDF–2.5M
13.
Diindolylamine Preparation and Stability Investigations
Geneviève N. Boice, Brian O. Patrick, Robin G. Hicks
ACS Omega. 2022 Feb 15; 7(6): 5197–5205. Published online 2022 Feb 4. doi: 10.1021/acsomega.1c06289
PMCID:
PMC8851611
ArticlePDF–1.6M
14.
Design and optimization of 1H-1,2,3-triazole-4-carboxamides as novel, potent, and selective inverse agonists and antagonists of PXR
Yongtao Li, Wenwei Lin, Sergio C. Chai, Jing Wu, Kavya Annu, Taosheng Chen
J Med Chem. Author manuscript; available in PMC 2023 Dec 22.
Published in final edited form as: J Med Chem. 2022 Dec 22; 65(24): 16829–16859. Published online 2022 Dec 8. doi: 10.1021/acs.jmedchem.2c01640
PMCID:
PMC9789209
ArticlePDF–2.8M
15.
Ornamenting of Blue Thermally Activated Delayed Fluorescence Emitters by Anchor Groups for the Minimization of Solid-State Solvation and Conformation Disorder Corollaries in Non-Doped and Doped Organic Light-Emitting Diodes
Malek Mahmoudi, Dalius Gudeika, Stepan Kutsiy, Jurate Simokaitiene, Rita Butkute, Levani Skhirtladze, Kai Lin Woon, Dmytro Volyniuk, Juozas Vidas Grazulevicius
ACS Appl Mater Interfaces. 2022 Sep 7; 14(35): 40158–40172. Published online 2022 Aug 24. doi: 10.1021/acsami.2c12475
PMCID:
PMC9460442
ArticlePDF–7.3M
16.
Functionalized C3-Symmetric Building Blocks—The Chemistry of Triaminotrimesic Acid
Lisa Schmidt, Danny Wagner, Martin Nieger, Stefan Bräse
Molecules. 2022 Jul; 27(14): 4369. Published online 2022 Jul 7. doi: 10.3390/molecules27144369
PMCID:
PMC9322044
ArticlePDF–3.5M
17.
Synthesis of Nonsymmetrically Substituted 2,3-Dialkoxyphenazine Derivatives and Preliminary Examination of Their Cytotoxicity
Paweł Ręka, Jarosław Grolik, Katarzyna M. Stadnicka, Maria Kołton-Wróż, Paweł Wołkow
J Org Chem. 2023 Feb 3; 88(3): 1339–1351. Published online 2023 Jan 13. doi: 10.1021/acs.joc.2c01901
PMCID:
PMC9903326
ArticlePDF–3.9M
18.
Diels–Alder Cycloaddition with CO, CO2, SO2, or N2 Extrusion: A Powerful Tool for Material Chemistry
Stanisław Krompiec, Aneta Kurpanik-Wójcik, Marek Matussek, Bogumiła Gołek, Angelika Mieszczanin, Aleksandra Fijołek
Materials (Basel) 2022 Jan; 15(1): 172. Published online 2021 Dec 27. doi: 10.3390/ma15010172
PMCID:
PMC8745824
ArticlePDF–136M
19.
Structure-Activity Relationship Studies to Identify Affinity Probes in Bis-aryl Sulfonamides that Prolong Immune Stimuli
Michael Chan, Fitzgerald S Lao, Paul J. Chu, Jonathan Shpigelman, Shiyin Yao, Jason Nan, Fumi Sato-Kaneko, Vicky Li, Tomoko Hayashi, Maripat Corr, Dennis A. Carson, Howard B. Cottam, Nikunj M. Shukla
J Med Chem. Author manuscript; available in PMC 2022 Apr 8.
Published in final edited form as: J Med Chem. 2019 Nov 14; 62(21): 9521–9540. Published online 2019 Oct 25. doi: 10.1021/acs.jmedchem.9b00870
PMCID:
PMC8992017
ArticlePDF–2.2M
20.
Design and synthesis of fungal-selective resorcylate aminopyrazole Hsp90 inhibitors
David S. Huang, Emmanuelle V. LeBlanc, Tanvi Shekhar-Guturja, Nicole Robbins, Damian J. Krysan, Juan Pizarro, Luke Whitesell, Leah E. Cowen, Lauren E. Brown
J Med Chem. Author manuscript; available in PMC 2021 Mar 12.
Published in final edited form as: J Med Chem. 2020 Mar 12; 63(5): 2139–2180. Published online 2019 Sep 26. doi: 10.1021/acs.jmedchem.9b00826
PMCID:
PMC7069776
ArticlePDF–2.3M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Search details

See more...

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center